Cholecystectomy promotes the development of colorectal cancer by the alternation of bile acid metabolism and the gut microbiota

The incidence and mortality of colorectal cancer (CRC) have been markedly increasing worldwide, causing a tremendous burden to the healthcare system.Therefore, it is crucial to investigate the risk factors and pathogenesis of CRC.Cholecystectomy is a gold standard procedure for treating symptomatic cholelithiasis and gallstone diseases.The rhythm o

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Tuning Ferulic Acid Solubility in Choline-Chloride- and Betaine-Based Deep Eutectic Solvents: Experimental Determination and Machine Learning Modeling

Deep eutectic solvents (DES) represent a promising class of green solvents, offering particular utility in the extraction and development of new formulations of natural compounds such as ferulic acid (FA).The experimental phase of the study undertook a systematic investigation of the solubility of FA in DES, comprising choline chloride or betaine a

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